Pearls, prepared, plate: Pearl oyster with pearl
Pearl oyster with pearl. E. W. Streeter, Pearls and Pearling Life (1886).
Save the plate to Pinterest

Pearls, prepared

Perle preparate

Known today as
Pearls ground to a fine powder.
Kind
Animal, in 1 older authority
Constituents
calcium carbonate, conchiolin, trace amino acids
Earliest authority here
Pliny (AD 23/24–79)
In the Canale glossary
On the Manner of Discerning and Healing the Bewitched, Appendix A: Part Three, Chapter 6: Remedies Given by Mouth After the Purge

Revised October 3, 2026: Checked against its sources, each read in full, in part, or in its abstract. Version 1, first published September 25, 2026.

Pearls, prepared: what did Canale use it for?

In the powder for the bewitched (ch. 6).

Pearls, prepared: what does modern science say?

Chemically almost all calcium carbonate, mostly as aragonite.

Pharmacognosy & Toxicology

Constituents
Mechanism
Ground pearl is calcium carbonate with a little protein, and a calcium source; the Chinese pearl powder (zhenzhu fen), given for the skin and to calm, has animal data for both: mice are sedated by it, its conchiolin protein seeming the key constituent, and scalds in mice heal faster under a pearl preparation.
Toxic dose
Safe taken over long periods without obvious adverse reactions; the Chinese Pharmacopoeia sets limits for its heavy metals.
Standing
In the Chinese Pharmacopoeia; a cosmetic ingredient; in Europe still used as a skin whitener in the nineteenth century.
  • Chinese Pharmacopoeia Commission (2020). Pharmacopoeia of the People’s Republic of China, “Margarita.” Primary text

Constituent names open the compound’s record at PubChem, and “ChEMBL” beside a name opens its record at ChEMBL, the European Bioinformatics Institute’s database of bioactive molecules. Where a mechanism line was checked against ChEMBL (ChEMBL 37, read 1 October 2026), the check is shown with the measured value and its source paper, or says plainly that nothing has been measured. Doses are as the references give them, for description only; this is not medical advice. Each source carries the result of its check against Crossref, PubMed, or the authority’s page: see Verification.

Used in These Compounds

Pearls, prepared is an ingredient of 2 compound medicines in the database. For Club members. Create a free account or sign in.

Pearls, prepared: what did the older authorities say?

Pliny
Tells how Cleopatra won a wager with Antony by dissolving a great pearl in vinegar and drinking it.

Sources

  • Pliny the Elder, Natural History 9.58–59, trans. J. Bostock & H. T. Riley (1855), Perseus Digital Library. Read in part · the text read
  • Wikipedia, “Pearl.” Read in full · the text read
  • Wikipedia, “Pearl powder.” Read in full · the text read
  • Song, Y., et al. (2022). The application of pearls in traditional medicine of China and their chemical constituents, pharmacology, toxicology, and clinical research. Frontiers in Pharmacology 13: 893229. Read in full · the text read

In Symbols of the Psyche

The Pearl: what it stood for in alchemy and in analytical psychology.

Verification

Checked
October 1, 2026, and October 3, 2026
Passes
  • Every sentence read against its sources, in the pass over the remaining 343 entries
  • The Standing line checked against the authority it names (EMA, WHO, FDA, CITES, Commission E)
  • Every dated or regulatory claim checked by category across the database
  • Every source read, in full, in part, or in its abstract, and every sentence checked against what was read (October 3, 2026)
Sources
5 cited: 3 read in full, 1 read in part, 1 primary text.
Corrections
None were needed.

What was checked, how, and what was found is set out on the Verification page. A checked source is one whose record was found; it does not make the entry medical advice.

Cite This Entry

Version 1 · first published September 25, 2026 · last revised October 3, 2026

Chicago

“Pearls, prepared.” In Materia Medica, edited by B. C. P. Statema. Version 1. The Thinking Press, 2026–. Last modified October 3, 2026. https://thethinkingpress.org/materia-medica/pearls-prepared.

MLA

“Pearls, prepared.” Materia Medica, edited by B. C. P. Statema, version 1, The Thinking Press, 3 Oct. 2026, thethinkingpress.org/materia-medica/pearls-prepared. Accessed 8 Oct. 2026.

APA

Pearls, prepared. (2026, October 3). In B. C. P. Statema (Ed.), Materia medica (Version 1). The Thinking Press. Retrieved October 8, 2026, from https://thethinkingpress.org/materia-medica/pearls-prepared

Download for Zotero, EndNote, or Mendeley: BibTeX · RIS

Club members keep entries on a shelf with private notes, print the plates as cards, and receive an entry by email each week. Create a free account before January 1, 2027 and all of it is yours for good. About the Club

See Also

Sharing calcium carbonate

Vine ash · Olive-wood ash lye · Woodlouse · Cuttlefish bone

Drawing on the same sources: Wikipedia

Quicksilver · Oak galls · Rose · the bibliography →

Nearby in the alphabet

Penicillin mould (fruit, and damp) · Pawpaw (the one temperate tree of the custard-apple family) · Passarino’s white powder (a man skilled in the spagyric (chemical) art (note XXXIX)) · Peony (the kind formerly grown for its medicinal root) · Paschal candle · Periwinkle (the lesser periwinkle, a trailing evergreen with blue flowers) · Parsley (Petroselinum crispum)

Historical description, not medical advice.