Peppermint
Brandy mint; Mentha × piperita of Linnaeus; the Mentha piperitis sapore, pepper-tasting mint, of the London Pharmacopoeia of 1721
- Known today as
- Mentha × piperita, a mint of moist places and stream banks across Europe, often escaped from cultivation, with stalked, finely toothed, nearly smooth leaves, square purplish stems two to four feet high, and whorls of small reddish-violet flowers that “rarely bear seeds.” Its oil, in every part of the plant, tastes hot on the tongue and then cold, “caused by the menthol it contains.” Leaf and distilled oil are both medicines.
- Kind
- Plant, in 2 older authorities
- Constituents
- menthol, menthone
- Earliest authority here
- Pliny, as Grieve reports him (AD 23/24–79)
Caution. The oil is not for people with liver disease, cholangitis, achlorhydria, gallstones, or other disorders of the bile ducts, and heartburn or hiatus hernia may worsen; the gut capsules must be swallowed whole, and antacids and acid-reducing drugs taken at the same time can release the oil too early. Menthol can cause reflex stoppage of breathing and spasm of the larynx in small children, so the oil is contraindicated under two years and in children with a history of seizures, and must not go on broken or irritated skin. Overdose can cause severe gut symptoms, convulsions, loss of consciousness, and disturbed heart rhythm. Use in pregnancy and breast-feeding is not recommended without medical advice.
Peppermint: what was it used for?
For the gut above all. “Peppermint oil is the most extensively used of all the volatile oils, both medicinally and commercially,” Grieve wrote, and its antispasmodic action, more marked than in any other oil, “greatly adds to its power of relieving pains arising in the alimentary canal”: dyspepsia, flatulence, colic, cramp, cholera and diarrhoea. It was given with purgatives to stop griping and used to disguise the taste of other drugs; the tea was taken at the first sign of a cold, and with elder flowers for influenza; menthol was rubbed on the temples for neuralgic headache and inhaled for the chest.
Peppermint: what does modern science say?
The European Medicines Agency’s herbal committee accepts peppermint oil on clinical evidence, as ‘well-established use’: for minor spasms of the gut, flatulence, and abdominal pain, “especially in patients with irritable bowel syndrome,” and for mild tension-type headache. For coughs and colds, local muscle pain, and itching of intact skin, and the leaf for indigestion and flatulence, it accepts traditional use only (monographs of 2020). The oil is chiefly menthol, 30 to 55 per cent, and menthone. A 2022 meta-analysis of ten trials in 1,030 patients with irritable bowel syndrome found the oil “superior to placebo,” but with more adverse events, and the quality of evidence “very low.” Pooled studies of oil given during colonoscopy found the colon relaxed, with fewer spasms.
Pharmacognosy & Toxicology
- Constituents
- Mechanism
- Pooled studies of the oil given during colonoscopy found the colon relaxed, with fewer spasms. Menthol can cause reflex stoppage of breathing and spasm of the larynx in small children.
- Standing
- European Union herbal monographs (2020): well-established use of the oil for gut spasm, especially in irritable bowel syndrome, and for tension headache; traditional use, “exclusively based upon long-standing use,” for other purposes and of the leaf.
- European Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Menthae piperitae aetheroleum (Peppermint oil). EMA/HMPC/522410/2013, 15 January 2020. Read in full · the text read
- European Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Menthae piperitae folium (peppermint leaf). EMA/HMPC/572705/2014, 15 January 2020. Read in full · the text read
- European Medicines Agency, Committee on Herbal Medicinal Products. Assessment report on Menthae piperitae folium. EMA/HMPC/522409/2013, 15 January 2020. Read in part · the text read
- Ingrosso MR, et al. (2022). Systematic review and meta-analysis: efficacy of peppermint oil in irritable bowel syndrome. Alimentary pharmacology & therapeutics. PMID 35942669. Abstract read · the text read
- Aziz M, et al. (2020). The anti-spasmodic effect of peppermint oil during colonoscopy: a systematic review and meta-analysis. Minerva gastroenterologica e dietologica. PMID 31994371. Abstract read · the text read
The abstract of each source, beneath its citation. For Club members. About the Club or sign in.
Constituent names open the compound’s record at PubChem, and “ChEMBL” beside a name opens its record at ChEMBL, the European Bioinformatics Institute’s database of bioactive molecules. Where a mechanism line was checked against ChEMBL (ChEMBL 37, read 1 October 2026), the check is shown with the measured value and its source paper, or says plainly that nothing has been measured. Doses are as the references give them, for description only; this is not medical advice. Each source carries the result of its check against Crossref, PubMed, or the authority’s page: see Verification.
Peppermint: what lore surrounds it?
The mints share a myth: the nymph Minthe, Folkard tells from Ovid, was beloved of Pluto, and Proserpine, finding out her husband’s infidelity, turned her into the herb that bears her name. Mint was herba bona and herba sancta of old, woven into garlands for brides, later dedicated to the Virgin; it was strewn in churches; women of the Abruzzi, meeting a mint plant on a walk, would bruise a leaf between their fingers to ensure that Christ would help them on the day of their death; and in Holstein youths carried mint at peasants’ funerals. Pliny held that “the smell of Mint doth stir up the minde and taste to a greedy desire of meat.”
Peppermint: what did the older authorities say?
- Pliny, as Grieve reports him
- The Greeks and Romans, she says, “crowned themselves with Peppermint at their feasts and adorned their tables with its sprays,” and their cooks flavoured sauces and wines with its essence; though she notes that some writers doubt whether either mint of the Greek physicians was the modern peppermint.
- Mrs. M. Grieve
- It is in the Icelandic pharmacopoeias of the thirteenth century, but only came into general use in western European medicine about the middle of the eighteenth, first in England. Ray first recognised it as a distinct species in 1696, and it entered the London Pharmacopoeia in 1721. Commercial growing at Mitcham in Surrey dates from about 1750, and “English oil is incomparably the best.”
Sources
- Grieve, M. A Modern Herbal, “Mints.” As published on botanical.com. Read in full · the text read
- Folkard, R. (1884). Plant Lore, Legends, and Lyrics, “Mint.” Project Gutenberg, 44638. Read in part · the text read
- European Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Menthae piperitae folium (peppermint leaf). EMA/HMPC/572705/2014, 15 January 2020. Read in full · the text read
- European Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Menthae piperitae aetheroleum (Peppermint oil). EMA/HMPC/522410/2013, 15 January 2020. Read in full · the text read
- European Medicines Agency, Committee on Herbal Medicinal Products. Assessment report on Menthae piperitae folium. EMA/HMPC/522409/2013, 15 January 2020. Read in part · the text read
- Ingrosso MR, et al. (2022). Systematic review and meta-analysis: efficacy of peppermint oil in irritable bowel syndrome. Alimentary pharmacology & therapeutics. PMID 35942669. Abstract read · the text read
- Aziz M, et al. (2020). The anti-spasmodic effect of peppermint oil during colonoscopy: a systematic review and meta-analysis. Minerva gastroenterologica e dietologica. PMID 31994371. Abstract read · the text read
Verification
- Checked
- October 1, 2026
- Passes
- Every sentence read against its sources, in the pass over the remaining 343 entries
- The Standing line checked against the authority it names (EMA, WHO, FDA, CITES, Commission E)
- Every dated or regulatory claim checked by category across the database
- Sources
- 7 cited: 3 read in full, 2 read in part, 2 abstract read. 2 with the abstract on file.
- Corrections
- None were needed.
What was checked, how, and what was found is set out on the Verification page. A checked source is one whose record was found; it does not make the entry medical advice.
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Cite This Entry
Version 1 · first published October 16, 2026
- Chicago
“Peppermint.” In Materia Medica, edited by B. C. P. Statema. Version 1. The Thinking Press, 2026–. Last modified October 16, 2026. https://thethinkingpress.org/materia-medica/peppermint.
- MLA
“Peppermint.” Materia Medica, edited by B. C. P. Statema, version 1, The Thinking Press, 16 Oct. 2026, thethinkingpress.org/materia-medica/peppermint. Accessed 17 Oct. 2026.
- APA
Peppermint. (2026, October 16). In B. C. P. Statema (Ed.), Materia medica (Version 1). The Thinking Press. Retrieved October 17, 2026, from https://thethinkingpress.org/materia-medica/peppermint
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See Also
Sharing menthol, menthone
Also in Pliny the Elder
Pilewort in Pliny the Elder · Pennyroyal in Pliny the Elder · Polypody of mercurialis, syrup of in Pliny the Elder · Pearls, prepared in Pliny the Elder · everything Pliny the Elder names →
Also in M. Grieve
Pokeweed in M. Grieve · Pawpaw in M. Grieve · Roman chamomile in M. Grieve · Pasque flower in M. Grieve · everything M. Grieve names →
Drawing on the same sources: Grieve, Folkard
Periwinkle · Peony · Pink rock-rose · Passionflower · Primrose · the bibliography →
Nearby in the alphabet
Picrorhiza · Penicillin mould (common in damp buildings, house dust, and spoiling food) · Pilgrim badges and ampullae · Pelargonium
Historical description, not medical advice.
