Cuttlefish bone

Os sepiae

Known today as
The chalky internal shell of the cuttlefish, washed up on beaches.
Kind
Animal, in 1 older authority
Constituents
calcium carbonate, chitin, organic matrix
Earliest authority here
Dioscorides (c. AD 40–90)

Cuttlefish bone: what was it used for?

Powdered, as a tooth powder, for spots on the eyes, and as an absorbent for the stomach.

Cuttlefish bone: what does modern science say?

Mostly calcium carbonate; it is given to caged birds for the calcium. It is an ingredient in Chinese medicine.

Pharmacognosy & Toxicology

Constituents
Mechanism
An antacid and a mild abrasive, which is the tooth powder; the “spots on the eyes” use was abrasion of a corneal scar, a practice that would do harm. Its porous aragonite is converted to hydroxyapatite in the laboratory as a bone-graft scaffold.
Toxic dose
Inert.
Standing
Sold for cage birds; a research biomaterial.
  • Rocha, J. H. G., et al. (2005). “Scaffolds for bone restoration from cuttlefish.” Bone 37. Verified against its record · doi:10.1016/j.bone.2005.06.018

The abstract of each source, beneath its citation. For Club members. About the Club or sign in.

Constituent names open the compound’s record at PubChem, and “ChEMBL” beside a name opens its record at ChEMBL, the European Bioinformatics Institute’s database of bioactive molecules. Where a mechanism line was checked against ChEMBL (ChEMBL 37, read 1 October 2026), the check is shown with the measured value and its source paper, or says plainly that nothing has been measured. Doses are as the references give them, for description only; this is not medical advice. Each source carries the result of its check against Crossref, PubMed, or the authority’s page: see Verification.

Cuttlefish bone: what did the older authorities say?

Dioscorides
Gives the burnt bone for the teeth and to clean the eyes.

Sources

Verification

Checked
October 1, 2026
Passes
  • Every sentence read against its sources, in the pass over the remaining 343 entries
  • The Standing line checked against the authority it names (EMA, WHO, FDA, CITES, Commission E)
  • Every dated or regulatory claim checked by category across the database
Sources
2 cited: 1 read in part, 1 verified against its record. 1 with the abstract on file.
Corrections
None were needed.

What was checked, how, and what was found is set out on the Verification page. A checked source is one whose record was found; it does not make the entry medical advice.

Cite This Entry

Version 1 · first published September 30, 2026

Chicago

“Cuttlefish bone.” In Materia Medica, edited by B. C. P. Statema. Version 1. The Thinking Press, 2026–. Last modified September 30, 2026. https://thethinkingpress.org/materia-medica/cuttlefish-bone.

MLA

“Cuttlefish bone.” Materia Medica, edited by B. C. P. Statema, version 1, The Thinking Press, 30 Sept. 2026, thethinkingpress.org/materia-medica/cuttlefish-bone. Accessed 8 Oct. 2026.

APA

Cuttlefish bone. (2026, September 30). In B. C. P. Statema (Ed.), Materia medica (Version 1). The Thinking Press. Retrieved October 8, 2026, from https://thethinkingpress.org/materia-medica/cuttlefish-bone

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See Also

Sharing calcium carbonate, chitin, organic matrix

Olive-wood ash lye · Crabs’ eyes · Pearls, prepared · Corallium rubrum · Woodlouse

Drawing on the same sources: Dioscorides

Garlic · the bibliography →

Nearby in the alphabet

Cyclamen, greater (Cyclamen purpurascens or C) · Cumin (Cuminum cyminum) · Cyclosporin fungus (A soil fungus) · Cubeb (a Javanese pepper whose berries keep a little stalk, like a tail) · Cypress (Cupressus sempervirens) · Crucifix (The image of Christ on the Cross) · Cyprus powder (a perfumed toilet powder)

Historical description, not medical advice.