Eucalyptus

Blue gum, fever tree, stringy bark tree; Eucalyptus globulus Labill.; in pharmacy Eucalypti folium, the leaf, and Eucalypti aetheroleum, the oil

Known today as
Eucalyptus globulus, the blue gum of Victoria and Tasmania, which Grieve says reaches 375 feet and ranks among the largest trees in the world. Young trees have broad, stalkless, whitish-green leaves set opposite and flat; after four or five years come sword-shaped, bluish leaves, “alternate and vertical, i.e. with the edges turned towards the sky and earth.” The flower bud wears a cap thrown off as a lid when it opens, whence the Greek name, well-covered. The leaves and the oil distilled from them are the medicines.
Kind
Plant, in 1 older authority
Constituents
1,8-cineole
Earliest authority here
King’s American Dispensatory
In other databases
Plants of the World Online · GBIF · Wikidata

Caution. The oil is dangerous to small children: the European agency contraindicates it under 24 months because, like other essential oils, cineole can cause spasm of the larynx, and in children with a history of seizures. A 2021 review of 110 published cases found seizures brought on by eucalyptus oil applied to the skin, inhaled, or swallowed, in children and adults. Taken by mouth in excess it can cause vomiting, breathing problems, loss of consciousness, and convulsions; it is not for broken or irritated skin, and it calls for caution in inflamed or ulcerated conditions of the gut. Grieve already warned that in large doses it depresses the nervous system and can stop the breathing.

Eucalyptus: what was it used for?

An antiseptic oil, above all. Grieve calls the medicinal oil “probably the most powerful antiseptic of its class, especially when it is old,” used as a stimulant and antiseptic gargle, inhaled for asthma, diphtheria, and sore throat, applied freely to the skin in croup, and given in drachm doses in tuberculosis and bronchitis. The trees themselves were planted against malaria: the botanist von Müller first suggested their scented leaves might disinfect fever districts, and in Algeria, Grieve says, a marshy, unhealthy district was made one of the healthiest within five years of planting, chiefly by the drying action of the roots.

Eucalyptus: what does modern science say?

The European Medicines Agency’s herbal committee accepts the oil as a traditional herbal medicine, “exclusively based upon long-standing use,” for the relief of cough associated with a cold and, rubbed on, for localised muscle pain (monograph of 2024), and the leaf for cough associated with a cold (monograph of 2013). The oil’s chief constituent is 1,8-cineole, also called eucalyptol, given in the leaf report as 54 to 95 per cent of the oil. A 2022 meta-analysis of trials for cough found eucalyptus products safe, but their efficacy “minimal and of uncertain clinical importance.”

Eucalyptus: is it poisonous?

Yes, in some form or dose. The oil is dangerous to small children: the European agency contraindicates it under 24 months because, like other essential oils, cineole can cause spasm of the larynx, and in children with a history of seizures. A 2021 review of 110 published cases found seizures brought on by eucalyptus oil applied to the skin, inhaled, or swallowed, in children and adults. Taken by mouth in excess it can cause vomiting, breathing problems, loss of consciousness, and convulsions; it is not for broken or irritated skin, and it calls for caution in inflamed or ulcerated conditions of the gut. Grieve already warned that in large doses it depresses the nervous system and can stop the breathing. Its poisoning is convulsant terpenes (thujone, pinocamphone, camphor): Minutes to an hour from the oils. Historical description, not medical advice; in a poisoning, call a poison centre.

Pharmacognosy & Toxicology

Constituents
Mechanism
Cineole, like other essential oils, can cause spasm of the larynx in small children; the oil has brought on seizures, applied to the skin, inhaled, or swallowed.
Syndrome
Convulsant terpenes (thujone, pinocamphone, camphor)
Standing
European Union herbal monographs: traditional use, “exclusively based upon long-standing use,” of the oil for cough with a cold and for muscle pain (2024), and of the leaf for cough with a cold (2013).
  • European Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Eucalypti aetheroleum (Eucalyptus Oil). EMA/HMPC/320292/2023, 20 November 2024. Read in full · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. Assessment report on Eucalypti folium. EMA/HMPC/892615/2011, 15 April 2013. Read in part · the text read
  • Panda PK, et al. (2021). Clinico-laboratory characteristics and outcome of patients with eucalyptus oil-induced/provoked seizures: A case series and systematic review of the published patients. Tropical doctor. PMID 34282989. Abstract read · the text read

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Constituent names open the compound’s record at PubChem, and “ChEMBL” beside a name opens its record at ChEMBL, the European Bioinformatics Institute’s database of bioactive molecules. Where a mechanism line was checked against ChEMBL (ChEMBL 37, read 1 October 2026), the check is shown with the measured value and its source paper, or says plainly that nothing has been measured. Doses are as the references give them, for description only; this is not medical advice. Each source carries the result of its check against Crossref, PubMed, or the authority’s page: see Verification.

Eucalyptus: what lore surrounds it?

Grieve reports that the name globulus was said to have been given by the French botanist Labillardière because the waxy fruit resembled a button then worn in France. In the Roman Campagna, she says, the monastery of St. Paolo à la tre Fontana, in one of the most fever-stricken districts, became habitable all the year after eucalyptus was planted in its cloisters about 1870, and the disappearance of mosquitoes near plantations was put down to the drainage of their roots.

Eucalyptus: what did the older authorities say?

King’s American Dispensatory
“The Eucalyptus trees are very numerous in their native country, and constitute an important feature in every landscape.” Most of them exude a resinous substance, “and hence are known to the Australian colonists as ‘gum trees,’” and their leaves, opposite and flat in the young tree, turn their edges to the ground in the old, “thus giving the Eucalyptus a strange appearance.”

Sources

  • Grieve, M. A Modern Herbal, “Eucalyptus.” As published on botanical.com. Read in full · the text read
  • Felter, H. W., & Lloyd, J. U. (1898). King’s American Dispensatory, vol. 1, “Eucalyptus.” Internet Archive, kingsamericandis01kinguoft. Read in part · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Eucalypti aetheroleum (Eucalyptus Oil). EMA/HMPC/320292/2023, 20 November 2024. Read in full · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Eucalypti folium (Eucalyptus leaf). EMA/HMPC/892618/2011, 15 April 2013. Read in full · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. Assessment report on Eucalypti aetheroleum. EMA/HMPC/320282/2023, 20 November 2024. Read in part · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. Assessment report on Eucalypti folium. EMA/HMPC/892615/2011, 15 April 2013. Read in part · the text read
  • Her L, et al. (2022). Efficacy and Safety of <i>Eucalyptus</i> for Relieving Cough: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of integrative and complementary medicine. PMID 35294302. Abstract read · the text read
  • Panda PK, et al. (2021). Clinico-laboratory characteristics and outcome of patients with eucalyptus oil-induced/provoked seizures: A case series and systematic review of the published patients. Tropical doctor. PMID 34282989. Abstract read · the text read

Verification

Checked
October 1, 2026
Passes
  • Every sentence read against its sources, in the pass over the remaining 343 entries
  • The Standing line checked against the authority it names (EMA, WHO, FDA, CITES, Commission E)
  • Every dated or regulatory claim checked by category across the database
Sources
8 cited: 3 read in full, 3 read in part, 2 abstract read. 2 with the abstract on file.
Corrections
None were needed.

What was checked, how, and what was found is set out on the Verification page. A checked source is one whose record was found; it does not make the entry medical advice.

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Cite This Entry

Version 1 · first published October 16, 2026

Chicago

“Eucalyptus.” In Materia Medica, edited by B. C. P. Statema. Version 1. The Thinking Press, 2026–. Last modified October 16, 2026. https://thethinkingpress.org/materia-medica/eucalyptus.

MLA

“Eucalyptus.” Materia Medica, edited by B. C. P. Statema, version 1, The Thinking Press, 16 Oct. 2026, thethinkingpress.org/materia-medica/eucalyptus. Accessed 17 Oct. 2026.

APA

Eucalyptus. (2026, October 16). In B. C. P. Statema (Ed.), Materia medica (Version 1). The Thinking Press. Retrieved October 17, 2026, from https://thethinkingpress.org/materia-medica/eucalyptus

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See Also

Poisoned alike: convulsant terpenes (thujone, pinocamphone, camphor)

Hungary water · Camphor · Hyssop · Wormwood, oil of · Mint, oil of · Tansy · Mugwort · Sage · the syndrome, with all of them →

Drawing on the same sources: Grieve, Felter

Evening primrose · Eryngo · Eyebright · Ghost pipe · Cubeb · Ground cherry · the bibliography →

Nearby in the alphabet

The exorcists’ manuals (above all those of the Franciscan Girolamo Menghi) · Ergot · The eye bead (white, light blue, and black, like an eye) · Epsom salt (the salt of the bitter purging waters near Epsom in Surrey) · Epithymum (Cuscuta epithymum, a parasitic plant)

Historical description, not medical advice.