Echinacea

Purple coneflower, American coneflower, Black Sampson, Rudbeckia; Echinacea purpurea (L.) Moench, with the narrow-leaved E. angustifolia DC. and the pale E. pallida (Nutt.) Nutt.; in pharmacy Echinaceae purpureae herba and radix, Echinaceae angustifoliae radix, Echinaceae pallidae radix

Known today as
The coneflowers of North America, of the family Asteraceae, whose rich purple florets are “seated round a high cone.” LiverTox counts at least nine species, of which Echinacea purpurea, pallida, and angustifolia are the most used, and gives E. purpurea as native to the United States east of the Rocky Mountains. Grieve, describing E. angustifolia from America west of Ohio, notes that its root has a faint aromatic smell and a sweetish taste, “leaving a tingling sensation in the mouth not unlike Aconitum napellus, but without its lasting numbing effect.”
Kind
Plant, in 1 older authority
Constituents
cichoric acid, echinacoside, alkamides, and 1 more
Earliest authority here
Grieve, A Modern Herbal (1931) (A Modern Herbal, 1931)
In other databases
Plants of the World Online · GBIF · Wikidata

Caution. Not for those allergic to plants of the Asteraceae (Compositae) family, and not recommended under twelve. The European agency advises against it in progressive systemic diseases such as tuberculosis, in diseases of the white blood cells, collagenoses, multiple sclerosis, HIV infection, and other immune diseases, and warns of a possible risk of severe allergic reactions in atopic patients. Rash, urticaria, and swelling of the face have been reported, and rarely severe reactions including Stevens-Johnson syndrome, bronchospasm, and anaphylactic shock; an association with autoimmune diseases cannot be excluded. Applied to the skin it can cause contact dermatitis, and it should not be applied to the breast of a breastfeeding woman. LiverTox finds it generally well tolerated, but records isolated reports of liver injury with jaundice, which recovered on stopping; it is unclear whether a particular species, preparation, or contaminant was to blame.

Echinacea: what was it used for?

A remedy, in Grieve’s words, that “increases bodily resistance to infection,” used for boils, erysipelas, septicaemia, and impurities of the blood, its action being antiseptic; a tincture of the fresh root was found beneficial in diphtheria and putrid fevers. Its modern use is chiefly against the common cold.

Echinacea: what does modern science say?

The European Medicines Agency’s herbal committee treats each species and part separately. It accepts the expressed juice of the herb of E. purpurea on clinical evidence, as ‘well-established use,’ for the short-term prevention and treatment of the common cold, and, as a traditional herbal medicine, for small superficial wounds (monograph of 2015). As traditional herbal medicines, “exclusively based upon long-standing use,” it accepts the root of E. purpurea for the symptoms of the common cold and for the spots and pimples of mild acne (2017), the root of E. angustifolia for supportive treatment of the common cold (2012), and the root of E. pallida for the symptoms of the common cold (2018). Its assessment reports name caffeic acid derivatives, cichoric acid chief in E. purpurea and echinacoside in the other two roots, with alkamides, polysaccharides, and a little volatile oil; the root of E. pallida is almost without alkamides. The trials are less clear than the regulator. A Cochrane review of 2014, of twenty-four trials in 4,631 participants, found that echinacea products “have not here been shown to provide benefits for treating colds,” though a weak benefit from some products is possible, and that no single prevention comparison was significant, a post hoc pooling suggesting a relative risk reduction of 10 to 20 per cent. A 2025 meta-analysis of nine trials in children found that E. purpurea shortened upper respiratory infections and reduced their incidence and the use of antibiotics, while judging its safety profile unclear.

Pharmacognosy & Toxicology

Constituents
Mechanism
Not established in the sources read for this entry.
Standing
European Union herbal monographs (2012 to 2018): well-established use of the expressed juice of E. purpurea herb for the common cold, and traditional use, “exclusively based upon long-standing use,” of the roots of three species. A Cochrane review (2014) found no clear benefit for treating colds.
  • European Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Echinaceae purpureae herba (Purple Coneflower Herb). EMA/HMPC/48704/2014 Corr 1, 24 November 2015. Read in full · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. Assessment report on Echinaceae purpureae herba. EMA/HMPC/557979/2013, 24 November 2014. Read in part · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. Assessment report on Echinaceae angustifoliae radix. EMA/HMPC/688212/2008, 27 March 2012. Read in part · the text read
  • Karsch-Völk M, et al. (2014). Echinacea for preventing and treating the common cold. The Cochrane database of systematic reviews. PMID 24554461. Abstract read · the text read
  • LiverTox: Clinical and Research Information on Drug-Induced Liver Injury, “Echinacea.” National Institute of Diabetes and Digestive and Kidney Diseases, updated 2019. NCBI Bookshelf. Read in full · the text read

The abstract of each source, beneath its citation. For Club members. About the Club or sign in.

Constituent names open the compound’s record at PubChem, and “ChEMBL” beside a name opens its record at ChEMBL, the European Bioinformatics Institute’s database of bioactive molecules. Where a mechanism line was checked against ChEMBL (ChEMBL 37, read 1 October 2026), the check is shown with the measured value and its source paper, or says plainly that nothing has been measured. Doses are as the references give them, for description only; this is not medical advice. Each source carries the result of its check against Crossref, PubMed, or the authority’s page: see Verification.

Echinacea: what lore surrounds it?

Grieve lists among its uses cancer and syphilis, and gives it “useful properties as a strong alterative and aphrodisiac”; she records too that an injection of the extract had been used for haemorrhoids.

Echinacea: what did the older authorities say?

Grieve, A Modern Herbal (1931)
The plant was named Echinacea by Linnaeus, and Rudbeckia after Rudbeck, father and son, his predecessors at Uppsala. Grieve’s chapter is on E. angustifolia, the dried root and rhizome; of E. purpurea she adds only that it “has similar properties,” the fresh root being the part used.

Sources

  • Grieve, M. A Modern Herbal, “Echinacea.” As published on botanical.com. Read in full · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Echinaceae purpureae herba (Purple Coneflower Herb). EMA/HMPC/48704/2014 Corr 1, 24 November 2015. Read in full · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Echinaceae purpureae radix (Purple Coneflower Root). EMA/HMPC/424583/2016, 30 May 2017. Read in full · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Echinaceae angustifoliae radix (Narrow-leaved coneflower root). EMA/HMPC/688216/2008, 27 March 2012. Read in full · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. European Union herbal monograph on Echinaceae pallidae radix (Pale Coneflower Root). EMA/HMPC/737380/2018, 05 June 2018. Read in full · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. Assessment report on Echinaceae purpureae herba. EMA/HMPC/557979/2013, 24 November 2014. Read in part · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. Assessment report on Echinaceae purpureae radix. EMA/HMPC/424584/2016, 30 May 2017. Read in part · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. Assessment report on Echinaceae angustifoliae radix. EMA/HMPC/688212/2008, 27 March 2012. Read in part · the text read
  • European Medicines Agency, Committee on Herbal Medicinal Products. Assessment report on Echinaceae pallidae radix. EMA/HMPC/737379/2017, 05 June 2018. Read in part · the text read
  • Karsch-Völk M, et al. (2014). Echinacea for preventing and treating the common cold. The Cochrane database of systematic reviews. PMID 24554461. Abstract read · the text read
  • Pham TP, et al. (2025). Efficacy and safety of Echinacea purpurea in treating upper respiratory infections and complications of otitis media in children: Systematic review and meta-analysis. Clinical nutrition ESPEN. PMID 40311928. Abstract read · the text read
  • LiverTox: Clinical and Research Information on Drug-Induced Liver Injury, “Echinacea.” National Institute of Diabetes and Digestive and Kidney Diseases, updated 2019. NCBI Bookshelf. Read in full · the text read

Verification

Checked
October 1, 2026
Passes
  • Every sentence read against its sources, in the pass over the remaining 343 entries
  • The Standing line checked against the authority it names (EMA, WHO, FDA, CITES, Commission E)
  • Every dated or regulatory claim checked by category across the database
Sources
12 cited: 6 read in full, 4 read in part, 2 abstract read. 2 with the abstract on file.
Corrections
None were needed.

What was checked, how, and what was found is set out on the Verification page. A checked source is one whose record was found; it does not make the entry medical advice.

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Cite This Entry

Version 1 · first published October 16, 2026

Chicago

“Echinacea.” In Materia Medica, edited by B. C. P. Statema. Version 1. The Thinking Press, 2026–. Last modified October 16, 2026. https://thethinkingpress.org/materia-medica/echinacea.

MLA

“Echinacea.” Materia Medica, edited by B. C. P. Statema, version 1, The Thinking Press, 16 Oct. 2026, thethinkingpress.org/materia-medica/echinacea. Accessed 17 Oct. 2026.

APA

Echinacea. (2026, October 16). In B. C. P. Statema (Ed.), Materia medica (Version 1). The Thinking Press. Retrieved October 17, 2026, from https://thethinkingpress.org/materia-medica/echinacea

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See Also

Drawing on the same sources: Grieve

Elder · Dragon’s blood · Elecampane · the bibliography →

Nearby in the alphabet

Earthworm (washed in wine, dried, powdered, or boiled in oil) · Earth of the Holy Land · Eleutherococcus (of the family Araliaceae, whose root is the medicine) · Eagle-stone (A hollow nodule of iron oxide with a loose stone rattling inside) · Elf-shot (Prehistoric flint arrowheads turned up in the fields)

Historical description, not medical advice.