Greek sage
Three-lobed sage; perhaps the ancient elelisphakon; Salvia triloba L.f.; Salvia fruticosa Mill.; in pharmacy Salviae trilobae folium
- Known today as
- Salvia fruticosa, an evergreen shrub of the family Lamiaceae up to a metre high, native to the eastern Mediterranean from Sicily and southern Italy and Cyrenaica through Greece to western Syria, and naturalised in Spain and Portugal, where the European Medicines Agency’s assessment report thinks it was probably brought by ancient navigators. It is told from garden sage by its leaves, sometimes with one or two small lobes at the base, densely felted, grey above and white beneath. The leaf’s essential oil is chiefly 1,8-cineole, with camphor and a little thujone.
- Kind
- Plant, in 1 older authority
- Constituents
- 1,8-cineole, camphor, thujone, and 2 more
- Earliest authority here
- The European Medicines Agency’s assessment report (2016)
- In other databases
- Plants of the World Online · GBIF · Wikidata
Caution. Conventional clinical safety data are absent, the assessment report notes, and it cannot be recommended by mouth under eighteen. The oil contains camphor and a little thujone.
Greek sage: what was it used for?
A tea for digestion and the blood. The assessment report gathers its folk uses: in Madeira for headache and as a blood purifier, in Spain as a stomachic, a tranquilliser, and a wound herb, elsewhere in the Mediterranean as a carminative, and in the Paphos district of Cyprus as a tea after heavy meals and a daily breakfast drink of diabetics.
Greek sage: what does modern science say?
The European Medicines Agency’s herbal committee declined to adopt a monograph on the leaf (public statement of 2016). It recognised the plant’s medicinal use in several member states but found the documented historical information “insufficient to verify the necessary conditions of a long-standing traditional use”: some preparations had been in medicinal use for more than fifteen years but less than thirty. Its assessment report finds rosmarinic acid, carnosic acid and carnosol, flavonoids, and triterpenes in the leaf besides the oil.
Pharmacognosy & Toxicology
- Constituents
- 1,8-cineole ChEMBLchief constituent of the leaf’s essential oil
- camphor ChEMBLin the oil
- thujone ChEMBLa little, in the oil
- rosmarinic acid ChEMBL
- carnosic acid ChEMBLwith carnosol
- Mechanism
- Not established in the sources read for this entry.
- Standing
- There is no European monograph: the European Medicines Agency’s herbal committee declined to adopt one (public statement of 2016).
- European Medicines Agency, Committee on Herbal Medicinal Products. Public statement on Salviae trilobae folium (Three-lobed sage leaf). EMA/HMPC/599993/2014, 31 May 2016. Read in full · the text read
- European Medicines Agency, Committee on Herbal Medicinal Products. Assessment report on Salviae trilobae folium. EMA/HMPC/599992/2014, 31 May 2016. Read in part · the text read
Constituent names open the compound’s record at PubChem, and “ChEMBL” beside a name opens its record at ChEMBL, the European Bioinformatics Institute’s database of bioactive molecules. Where a mechanism line was checked against ChEMBL (ChEMBL 37, read 1 October 2026), the check is shown with the measured value and its source paper, or says plainly that nothing has been measured. Doses are as the references give them, for description only; this is not medical advice. Each source carries the result of its check against Crossref, PubMed, or the authority’s page: see Verification.
Greek sage: what did the older authorities say?
- The European Medicines Agency’s assessment report (2016)
- Archaeological evidence suggests that the plant, hidden among the ancient authors under the general name elelisphakon, has probably been used medicinally since 1400 BC; mistranslating that word as the garden sage, S. officinalis, may have cost Greek sage its medicinal reputation and given garden sage uses that probably belonged to it.
Sources
- European Medicines Agency, Committee on Herbal Medicinal Products. Public statement on Salviae trilobae folium (Three-lobed sage leaf). EMA/HMPC/599993/2014, 31 May 2016. Read in full · the text read
- European Medicines Agency, Committee on Herbal Medicinal Products. Assessment report on Salviae trilobae folium. EMA/HMPC/599992/2014, 31 May 2016. Read in part · the text read
Verification
- Checked
- October 1, 2026
- Passes
- Every sentence read against its sources, in the pass over the remaining 343 entries
- The Standing line checked against the authority it names (EMA, WHO, FDA, CITES, Commission E)
- Every dated or regulatory claim checked by category across the database
- Sources
- 2 cited: 1 read in full, 1 read in part.
- Corrections
- None were needed.
What was checked, how, and what was found is set out on the Verification page. A checked source is one whose record was found; it does not make the entry medical advice.
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Cite This Entry
Version 1 · first published October 17, 2026
- Chicago
“Greek sage.” In Materia Medica, edited by B. C. P. Statema. Version 1. The Thinking Press, 2026–. Last modified October 17, 2026. https://thethinkingpress.org/materia-medica/greek-sage.
- MLA
“Greek sage.” Materia Medica, edited by B. C. P. Statema, version 1, The Thinking Press, 17 Oct. 2026, thethinkingpress.org/materia-medica/greek-sage. Accessed 17 Oct. 2026.
- APA
Greek sage. (2026, October 17). In B. C. P. Statema (Ed.), Materia medica (Version 1). The Thinking Press. Retrieved October 17, 2026, from https://thethinkingpress.org/materia-medica/greek-sage
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See Also
Sharing 1,8-cineole, camphor, thujone
Laurus nobilis · Alpinia officinarum · Mint, oil of · Eucalyptus globulus · Artemisia vulgaris · Cinnamomum camphora · Paregoric · Vinegar of the four thieves
Nearby in the alphabet
Grindelia · Greater celandine (Chelidonium majus) · Ground cherry (the ground cherries) · Gorse (Ulex europaeus) · Ground ivy (Glechoma hederacea) · Goldenseal · Ground pine (yellow bugle, distinct from arthritica (note XLIX)) · Goldenrod
Historical description, not medical advice.


