Mastic

Mastiche; the tears of Chios

Known today as
The resin of Pistacia lentiscus, gathered almost only on the Greek island of Chios, in pale, brittle tears.
Kind
Resin & Wood, in 1 older authority
Constituents
masticadienonic acid, alpha-pinene
Earliest authority here
Dioscorides (c. AD 40–90)

Mastic: what was it used for?

Chewed to sweeten the breath and strengthen the gums; for the stomach and liver; in plasters, and as a varnish.

Mastic: what does modern science say?

Mastic gum has shown activity against Helicobacter pylori in early studies, and European regulators accept it as a traditional remedy for indigestion.

Pharmacognosy & Toxicology

Constituents
Mechanism
The resin’s triterpenes kill Helicobacter pylori in the dish; a small trial found it reduced the bacterium in patients without eradicating it.
Toxic dose
No toxicity.
Standing
Approved by the European Medicines Agency in 2015 as a traditional remedy for mild dyspepsia and skin inflammation.
  • Huwez, F. U., et al. (1998). “Mastic gum kills Helicobacter pylori.” New England Journal of Medicine 339. Verified against its record · doi:10.1056/nejm199812243392618
  • Dabos, K. J., et al. (2010). “The effect of mastic gum on Helicobacter pylori: a randomized pilot study.” Phytomedicine 17. Verified against its record · doi:10.1016/j.phymed.2009.09.010

Constituent names open the compound’s record at PubChem, and “ChEMBL” beside a name opens its record at ChEMBL, the European Bioinformatics Institute’s database of bioactive molecules. Where a mechanism line was checked against ChEMBL (ChEMBL 37, read 1 October 2026), the check is shown with the measured value and its source paper, or says plainly that nothing has been measured. Doses are as the references give them, for description only; this is not medical advice. Each source carries the result of its check against Crossref, PubMed, or the authority’s page: see Verification.

Mastic: what lore surrounds it?

The English word “masticate” has been linked to it, the gum being chewed.

Mastic: what did the older authorities say?

Dioscorides
Praises the Chian mastic above all other resins, for the stomach and for the teeth.

Sources

  • Dioscorides, De materia medica. Read in part · the text read
  • Pomet, P. (1694). Histoire générale des drogues (English, A Compleat History of Druggs, 1712). Read in part · the text read

Verification

Checked
October 1, 2026
Passes
  • Every sentence read against its sources, in the fifty-entry sample
  • The Standing line checked against the authority it names (EMA, WHO, FDA, CITES, Commission E)
  • Every dated or regulatory claim checked by category across the database
Sources
4 cited: 2 read in part, 2 verified against its record.
Corrections
None were needed.

What was checked, how, and what was found is set out on the Verification page. A checked source is one whose record was found; it does not make the entry medical advice.

Cite This Entry

Version 1 · first published September 30, 2026

Chicago

“Mastic.” In Materia Medica, edited by B. C. P. Statema. Version 1. The Thinking Press, 2026–. Last modified September 30, 2026. https://thethinkingpress.org/materia-medica/mastic.

MLA

“Mastic.” Materia Medica, edited by B. C. P. Statema, version 1, The Thinking Press, 30 Sept. 2026, thethinkingpress.org/materia-medica/mastic. Accessed 8 Oct. 2026.

APA

Mastic. (2026, September 30). In B. C. P. Statema (Ed.), Materia medica (Version 1). The Thinking Press. Retrieved October 8, 2026, from https://thethinkingpress.org/materia-medica/mastic

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See Also

Drawing on the same sources: Dioscorides, Pomet

Sal ammoniac · Saltpetre · the bibliography →

Nearby in the alphabet

Mayapple · Masterwort and angelica (Peucedanum ostruthium and Angelica archangelica) · Marking-nut electuary (Semecarpus anacardium (note XLIV)) · Meadowsweet · Marigold (the pot marigold)

Historical description, not medical advice.