Litharge

Lithargyrum, “silver stone”

Known today as
Lead monoxide, a byproduct of refining silver.
Kind
Mineral, in 1 older authority
Constituents
lead oxide
Earliest authority here
Menecrates
In other databases
Wikidata search

Caution. Poisonous.

Litharge: what was it used for?

The base of plasters, above all the diachylon plaster, and of drying ointments.

Litharge: what does modern science say?

Poisonous; its plasters were used into the twentieth century.

Litharge: is it poisonous?

Yes, in some form or dose. Poisonous. Its poisoning is mercury, arsenic, lead, and antimony: Minutes to hours for a large dose; months or years for the slow poisoning of the trades. Historical description, not medical advice; in a poisoning, call a poison centre.

Pharmacognosy & Toxicology

Constituents
Mechanism
As white lead.
Toxic dose
Chronic.
Syndrome
Mercury, arsenic, lead, and antimony
Standing
No medicinal use; the lead plaster of the pharmacopoeias is gone.
  • Needleman, H. (2004). Annual Review of Medicine 55. Book, not indexed

Constituent names open the compound’s record at PubChem, and “ChEMBL” beside a name opens its record at ChEMBL, the European Bioinformatics Institute’s database of bioactive molecules. Where a mechanism line was checked against ChEMBL (ChEMBL 37, read 1 October 2026), the check is shown with the measured value and its source paper, or says plainly that nothing has been measured. Doses are as the references give them, for description only; this is not medical advice. Each source carries the result of its check against Crossref, PubMed, or the authority’s page: see Verification.

Litharge: what did the older authorities say?

Menecrates
The diachylon plaster of litharge and oil was credited to Menecrates, physician to the emperor Tiberius.

Sources

  • Dioscorides, De materia medica V. Primary text

Verification

Checked
October 1, 2026
Passes
  • Every sentence read against its sources, in the pass over the remaining 343 entries
  • The Standing line checked against the authority it names (EMA, WHO, FDA, CITES, Commission E)
  • Every dated or regulatory claim checked by category across the database
Sources
2 cited: 1 primary text, 1 book, not indexed.
Corrections
None were needed.

What was checked, how, and what was found is set out on the Verification page. A checked source is one whose record was found; it does not make the entry medical advice.

Cite This Entry

Version 1 · first published September 25, 2026

Chicago

“Litharge.” In Materia Medica, edited by B. C. P. Statema. Version 1. The Thinking Press, 2026–. Last modified September 25, 2026. https://thethinkingpress.org/materia-medica/litharge.

MLA

“Litharge.” Materia Medica, edited by B. C. P. Statema, version 1, The Thinking Press, 25 Sept. 2026, thethinkingpress.org/materia-medica/litharge. Accessed 8 Oct. 2026.

APA

Litharge. (2026, September 25). In B. C. P. Statema (Ed.), Materia medica (Version 1). The Thinking Press. Retrieved October 8, 2026, from https://thethinkingpress.org/materia-medica/litharge

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See Also

Sharing lead oxide

Glass powder

Drawing on the same sources: Dioscorides, Needleman

Madonna lily · Lavender · Mandrake · White lead · the bibliography →

Nearby in the alphabet

Liverwort, or hepatica (Hepatica nobilis (syn) · Lion’s mane (A single clump of hanging spines on hardwood trees) · Livid pinkgill (of broadleaf woods) · Licorice (The root of Glycyrrhiza glabra) · Lodestone (naturally magnetic iron ore) · Letters from Heaven · Long pepper (The catkin-like fruit of Piper longum) · Lesser bean-trefoil (Anagyris foetida, a Mediterranean shrub)

Historical description, not medical advice.