Soapwort
Soaproot, bouncing Bet, latherwort, fuller’s herb, bruisewort, sopewort, crow soap, sweet Betty, wild sweet William; Greek strouthion; Latin radix, herba lanaria; Saponaria officinalis L.
- Known today as
- Saponaria officinalis, of the family Caryophyllaceae, a stout perennial of central and southern Europe, grown in English gardens, with smooth lance-shaped leaves and loose clusters of large pink flowers, often double, from July to September. The root and leaves are the drug. Grieve gives saponin as the chief constituent of the root, and notes its taste: bitter and slightly sweet, then a persistent pungency and a numbness in the mouth.
- Kind
- Plant, in 2 older authorities
- Constituents
- saponin
- Earliest authority here
- Dioscorides, De materia medica (1st century), book 2 (c. AD 40–90)
- In other databases
- Plants of the World Online · GBIF · Wikidata
Caution. Grieve warned that it “should be very cautiously used owing to its saponin content,” and Dioscorides that it could cause abortion. None of the sources read for this entry reports on its safety in modern use.
Soapwort: what was it used for?
A washing plant first and a medicine second. Dioscorides knew it as the herb “which fullers use for cleaning their wool.” As a medicine Grieve records a decoction for the itch, and the plant as tonic, diaphoretic, and alterative, used in jaundice, rheumatism, skin complaints, and “old venereal complaints,” especially where mercury had failed; it is also sternutatory, provoking sneezing.
Soapwort: what does modern science say?
No European monograph covers it, and the searches of Europe PMC made for this entry found no clinical trial of it as a medicine. Its saponins are now laboratory material: a 2026 study isolated new saponins from the root and found that one of them strongly increased the killing power of saporin, a protein toxin, against breast-cancer cells in culture, as a way of carrying protein drugs into cells.
Pharmacognosy & Toxicology
- Constituents
- saponinthe chief constituent of the root
- Mechanism
- In a 2026 laboratory study one of its saponins strongly increased the toxicity of the protein toxin saporin to breast-cancer cells in culture.
- Standing
- There is no European monograph, and no clinical trial of it as a medicine was found for this entry.
- Grieve, M. A Modern Herbal, “Soapwort.” As published on botanical.com. Read in full · the text read
- Lim-Paik C, et al. (2026). Improving Cytotoxicity of Saporin with Saponin SO1406 Isolated from the Roots of Saponaria Officinalis. Biomedicines. PMID 41898273. Abstract read · the text read
The abstract of each source, beneath its citation. For Club members. About the Club or sign in.
Constituent names open the compound’s record at PubChem, and “ChEMBL” beside a name opens its record at ChEMBL, the European Bioinformatics Institute’s database of bioactive molecules. Where a mechanism line was checked against ChEMBL (ChEMBL 37, read 1 October 2026), the check is shown with the measured value and its source paper, or says plainly that nothing has been measured. Doses are as the references give them, for description only; this is not medical advice. Each source carries the result of its check against Crossref, PubMed, or the authority’s page: see Verification.
Soapwort: what did the older authorities say?
- Dioscorides, De materia medica (1st century), book 2
- Dioscorides calls the root sharp and diuretic, and gives it with honey for disorders of the liver, coughs, and asthma, with other roots to break and pass stones and soften a hard spleen, and as a plaster for leprosy; it induced sneezing, and put up into the nostrils with honey it purged through the mouth. He adds that applied below it brings on menstruation and is an abortifacient. The translators of the modern English version identify his strouthion as soapwort.
- Culpeper, The Complete Herbal (1653)
- Under “Sopewort, or Bruisewort,” a plant of Venus, Culpeper records that country people bruised the leaves and laid them on cut fingers, hands, or legs to heal them, and that some boasted of it as a diuretic for stone and dropsy and extolled it as an absolute cure of the French pox, better than sarsaparilla or guaiacum; “which, how true it is, I leave others to judge.”
Sources
- Grieve, M. A Modern Herbal, “Soapwort.” As published on botanical.com. Read in full · the text read
- Dioscorides. De materia medica, 2-193, in the modern English version of T. A. Osbaldeston and R. P. A. Wood (Johannesburg: Ibidis, 2000), after Goodyer’s translation of 1655. Internet Archive. Read in part · the text read
- Culpeper, N. The Complete Herbal, “SOPEWORT, OR BRUISEWORT.” Project Gutenberg, 49513. Read in part · the text read
- Lim-Paik C, et al. (2026). Improving Cytotoxicity of Saporin with Saponin SO1406 Isolated from the Roots of Saponaria Officinalis. Biomedicines. PMID 41898273. Abstract read · the text read
Verification
- Checked
- October 1, 2026
- Passes
- Every sentence read against its sources, in the pass over the remaining 343 entries
- The Standing line checked against the authority it names (EMA, WHO, FDA, CITES, Commission E)
- Every dated or regulatory claim checked by category across the database
- Sources
- 4 cited: 1 read in full, 2 read in part, 1 abstract read. 1 with the abstract on file.
- Corrections
- None were needed.
What was checked, how, and what was found is set out on the Verification page. A checked source is one whose record was found; it does not make the entry medical advice.
Club members can point at a technical term in this entry, such as a constituent, an action, or a word of Jung’s, to read its definition from the source. The Club.
Cite This Entry
Version 1 · first published October 17, 2026
- Chicago
“Soapwort.” In Materia Medica, edited by B. C. P. Statema. Version 1. The Thinking Press, 2026–. Last modified October 17, 2026. https://thethinkingpress.org/materia-medica/soapwort.
- MLA
“Soapwort.” Materia Medica, edited by B. C. P. Statema, version 1, The Thinking Press, 17 Oct. 2026, thethinkingpress.org/materia-medica/soapwort. Accessed 17 Oct. 2026.
- APA
Soapwort. (2026, October 17). In B. C. P. Statema (Ed.), Materia medica (Version 1). The Thinking Press. Retrieved October 17, 2026, from https://thethinkingpress.org/materia-medica/soapwort
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See Also
Sharing saponin
Dioscorea villosa · Primula vulgaris · Caulophyllum thalictroides
Also in Dioscorides
Sorrel, syrup of in Dioscorides · Saffron in Dioscorides · Southernwood in Dioscorides · Rue in Dioscorides · everything Dioscorides names →
Also in Nicholas Culpeper
Solomon’s seal in Nicholas Culpeper · Shepherd’s purse in Nicholas Culpeper · Self-heal in Nicholas Culpeper · everything Nicholas Culpeper names →
Drawing on the same sources: Grieve, Culpeper
Nearby in the alphabet
Slippery elm · Soya · Skullcap
Historical description, not medical advice.

