Periwinkle

Vinca, pervinca; sorcerer’s violet

Known today as
Vinca minor, the lesser periwinkle, a trailing evergreen with blue flowers.
Kind
Plant, in 1 older authority
Constituents
vincamine, vinpocetine
Earliest authority here
Culpeper (1616–1654)

Periwinkle: what was it used for?

An astringent, for bleeding, fluxes, and cramps; the leaves chewed for toothache.

Periwinkle: what does modern science say?

Vinca minor yields vincamine, from which a drug for the circulation of the brain was made. The cancer drugs vincristine and vinblastine come from another plant, the Madagascar periwinkle, Catharanthus roseus.

Pharmacognosy & Toxicology

Constituents
Mechanism
Vincamine dilates the blood vessels of the brain; vinpocetine, made from it in Hungary in the 1970s, is sold for memory in Europe and Japan on thin evidence. The cancer drugs vincristine and vinblastine come from the Madagascar periwinkle, a different plant.
Toxic dose
Vinpocetine drops blood pressure and is not for pregnancy; the FDA warned in 2019.
Standing
Vinpocetine is a prescription drug in some countries and an unapproved supplement in the United States.
  • Szatmári, S. Z., and Whitehouse, P. J. (2003). “Vinpocetine for cognitive impairment and dementia.” Cochrane Database of Systematic Reviews. Verified against its record · doi:10.1002/14651858.cd003119

The abstract of each source, beneath its citation. For Club members. About the Club or sign in.

Constituent names open the compound’s record at PubChem, and “ChEMBL” beside a name opens its record at ChEMBL, the European Bioinformatics Institute’s database of bioactive molecules. Where a mechanism line was checked against ChEMBL (ChEMBL 37, read 1 October 2026), the check is shown with the measured value and its source paper, or says plainly that nothing has been measured. Doses are as the references give them, for description only; this is not medical advice. Each source carries the result of its check against Crossref, PubMed, or the authority’s page: see Verification.

Periwinkle: what lore surrounds it?

In France the “sorcerer’s violet”; in medieval England a garland of periwinkle was put on the condemned on the way to execution, and a medieval book of secrets attributed to Albertus Magnus gives it, powdered with earthworms, to kindle love between husband and wife.

Periwinkle: what did the older authorities say?

Culpeper
Places it under Venus, and says the leaves eaten together by man and wife cause love between them.

Sources

  • Grieve, M. (1931). A Modern Herbal, “Periwinkle.” Book, not indexed
  • Culpeper, N. (1652). The English Physitian. Primary text
  • The Book of Secrets of Albertus Magnus (attributed). Book, seen in reviews

Verification

Checked
October 1, 2026
Passes
  • Every sentence read against its sources, in the pass over the remaining 343 entries
  • The Standing line checked against the authority it names (EMA, WHO, FDA, CITES, Commission E)
  • Every dated or regulatory claim checked by category across the database
Sources
4 cited: 1 verified against its record, 1 primary text, 1 book, seen in reviews, 1 book, not indexed. 1 with the abstract on file.
Corrections
None were needed.

What was checked, how, and what was found is set out on the Verification page. A checked source is one whose record was found; it does not make the entry medical advice.

Cite This Entry

Version 1 · first published September 30, 2026

Chicago

“Periwinkle.” In Materia Medica, edited by B. C. P. Statema. Version 1. The Thinking Press, 2026–. Last modified September 30, 2026. https://thethinkingpress.org/materia-medica/periwinkle.

MLA

“Periwinkle.” Materia Medica, edited by B. C. P. Statema, version 1, The Thinking Press, 30 Sept. 2026, thethinkingpress.org/materia-medica/periwinkle. Accessed 8 Oct. 2026.

APA

Periwinkle. (2026, September 30). In B. C. P. Statema (Ed.), Materia medica (Version 1). The Thinking Press. Retrieved October 8, 2026, from https://thethinkingpress.org/materia-medica/periwinkle

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See Also

Drawing on the same sources: Grieve, Culpeper

Pilewort · Pennyroyal · Plantain · The precious stones · the bibliography →

Nearby in the alphabet

Peony (the kind formerly grown for its medicinal root) · Pilgrim badges and ampullae · Penicillin mould (fruit, and damp) · Poison fire coral (finger-like fungus of Japan, Korea, and Southeast Asia) · Pearls, prepared (Pearls ground to a fine powder)

Historical description, not medical advice.