A poisoning syndrome

Hepatotoxic monoterpenes (pulegone)

Pulegone in pennyroyal oil, and in lesser degree the oils of the mints.

Hepatotoxic monoterpenes (pulegone): how soon does it show?

Hours.

How does it run?

Vomiting, then liver failure, from the metabolite menthofuran; ten millilitres of the oil have killed.

What is done for it?

Acetylcysteine, as for paracetamol; supportive care.

Historical and descriptive, not medical advice. In a poisoning, call a poison centre or emergency services.

Which substances in the database cause it?

Plant ParsleyGreek selinon, petroselinon Petroselinum crispum.Caution
Pennyroyal (Mentha pulegium), plate: Pennyroyal
PlantPennyroyalPulegio Mentha pulegium.CanaleCaution
Rue (Ruta graveolens), plate: Rue
Plant RueRuta Ruta graveolens, garden rue.CanaleCaution
Savin (Juniperus sabina), plate: Savin
PlantSavinSabina Juniperus sabina, a low juniper.CanaleCaution
Water germander (Teucrium scordium), plate: Water germander
PlantWater germanderScordeo Teucrium scordium, of the same genus as wall germander, which has caused liver failure in modern herbal preparations.CanaleCaution

Sources