Taxine cardiotoxicity
The taxine alkaloids of the yew, taxine B above all. Not a cardiac glycoside: the taxines block the sodium and calcium channels of the heart cell rather than its sodium pump, so the yew keeps its own group.
Taxine cardiotoxicity: how soon does it show?
Hours.
How does it run?
Nausea and dizziness, then a slowed and irregular heart; death within hours by arrhythmia, often with no warning.
What is done for it?
There is no specific antidote; what is done is supportive, for the heart, in hospital.
Historical and descriptive, not medical advice. In a poisoning, call a poison centre or emergency services.
Which substances in the database cause it?
Sources
- Nelson, L. S., et al. (2007). Handbook of Poisonous and Injurious Plants, 2nd ed. Verified against its record · doi:10.1007/978-1-4939-8926-3
